Wednesday, January 15, 2025

Molbio Diagnostics redefines molecular diagnostics with Truenat: Shiva Sriram, President of Molbio Diagnostics




In a world marked by significant healthcare disparities and the rising burden of infectious diseases, innovation is the need of the hour.

Molbio Diagnostics has redefined the landscape of molecular diagnostics with its flagship product, Truenat. This portable, battery-operated molecular diagnostic platform has not only transformed the detection of tuberculosis (TB) but has also evolved into a versatile tool for diagnosing multiple diseases, including Covid-19.

At COP29 in Azerbaijan, Molbio Diagnostics further demonstrated its commitment to global health equity by linking climate change and TB in a pioneering discussion. The company’s donation of innovative diagnostic tools to Azerbaijan reinforced its mission to support sustainable and decentralized healthcare solutions.

Shiva Sriram, President of Molbio Diagnostics, in an exclusive interview with Shardul Nautiyal, shares insights into Truenat’s success story, the challenges of healthcare access, and Molbio’s broader vision for the future.

“Truenat's journey exemplifies a mission to provide affordable, high-quality diagnostics to underserved populations, addressing the healthcare needs of lower- and middle-income countries. With its ability to deliver rapid results within an hour, even in resource-limited settings, Truenat is a testament to the power of innovation in bridging healthcare gaps,” he stated.

Excerpts:

India has a high TB burden, which was a key focus at our conference. Laboratories often take time to process and send results. Could you elaborate on molecular testing and benefits of using Truenat?

Truenat is a rapid, point-of-care molecular diagnostic platform that miniaturizes real-time PCR technology. Traditionally, molecular testing required centralized labs, complex infrastructure, and highly trained personnel, making it inaccessible in remote areas. With Truenat, we’ve addressed these barriers by creating a portable, battery-operated device that requires minimal training and infrastructure.

This innovation enables molecular testing at the primary care level, providing early diagnosis and intervention. Results are available within an hour of sample processing, allowing immediate, evidence-based treatment. This is a significant shift from using molecular diagnostics merely as a confirmatory tool to making them the first line of testing. Additionally, Truenat’s solar-powered option ensures functionality in areas with limited or no electricity.

 

Molbio Diagnostics is committed to bringing healthcare closer to people. Can you expand on this mission?

Our mission is to ensure that no individual, irrespective of their socioeconomic status or geography, is deprived of quality healthcare. Globally, around 80 per cent of the population in lower- and middle-income countries lacks access to basic diagnostics. By miniaturizing advanced diagnostic technology and decentralizing healthcare, we’re breaking barriers to access. Truenat’s deployment in underserved regions allows patients to receive timely and accurate diagnoses without traveling long distances.

 

At COP29, Molbio Diagnostics donated innovative diagnostic tools to Azerbaijan. Could you speak about this initiative?

Azerbaijan hosted COP29 in Baku, where the connection between climate change and TB was a focal point. Changing climate patterns exacerbate TB through increased malnutrition, migration, and population density. The "TB Go Green" campaign, adopted by Azerbaijan, aligns with this perspective.

Molbio donated the Truenat platform, ProRad ATLAS ultra-portable X-ray system, and Truelux solar charging station to support Azerbaijan’s decentralized healthcare initiatives. This donation helps transition the country from centralized microscopy to rapid molecular testing, ensuring early diagnosis and intervention. Such efforts reflect our commitment to enabling sustainable and climate-resilient healthcare solutions.

 

Could you elaborate on Molbio’s state-of-the-art facility and its approach to quality?

Manufacturing healthcare products demands the highest quality standards. At Molbio, we’ve implemented robust quality management systems to ensure product consistency and reliability. Our facilities are equipped with dedicated teams for R&D, manufacturing, quality control, and assurance. We also maintain a logistics network to ensure seamless delivery and provide extensive training for service providers to guarantee prompt maintenance and support.

 

What is the average lifespan of a Truenat device, and how do you handle equipment breakdowns?

Truenat devices have an average lifespan of five to seven years, with many operating beyond a decade. Their solid-state design minimizes breakdowns and eliminates the need for annual calibrations. In case of equipment issues, we have a global network of trained service engineers to ensure timely repairs. Training programs conducted in India prepare these engineers to provide comprehensive on-ground support.

 

What other innovative tools Molbio developing?

Beyond Truenat, we’ve introduced tools like the ProRad ATLAS, an ultra-portable digital X-ray system for mass TB screening, and Thermalytics, a touch-free, AI-driven breast cancer screening device. These innovations address critical gaps in healthcare. For example, Thermalytics provides a pain-free, radiation-free solution for early breast cancer detection, ensuring privacy and comfort for patients.

 

Truenat is a multi-disease platform. Could you expand on its versatility?

Truenat’s modular design allows it to test for a wide range of infectious diseases - from TB and Covid-19 to malaria, dengue, and hepatitis - using different cartridges. It supports multiple sample types, making it a comprehensive diagnostic tool that strengthens healthcare systems once deployed.

 

How does Molbio collaborate with universities and startups?

We’ve launched the EDGE programme to support startups and universities working on healthcare innovations. Through mentorship and financial support, we help bring their ideas to commercialization and scale. Additionally, we offer internship opportunities at our R&D facilities to foster collaboration and innovation.

 

How can science and innovation mitigate the effects of climate change on disease transmission?

The Covid-19 pandemic taught us that multi-stakeholder collaboration is essential. Governments, NGOs, civil society, and the private sector must work together to address healthcare challenges. With ongoing climate change, such collaborations are crucial for creating resilient healthcare systems.

Molbio Diagnostics exemplifies the transformative potential of innovation and collaboration in healthcare. By decentralizing diagnostics and making cutting-edge tools accessible to the last mile, the company is paving the way for equitable, sustainable healthcare solutions.

(Source: www.pharmabiz.com)

 

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